Play Ozzy & Drix (U)(Independent) Online
Punch viruses as a tiny white blood cell while your pill buddy freezes enemies—navigating grossly charming guts and solving puzzles with that same weird energy as the cartoon. The brawling feels oddly good, and the buddy-cop banter keeps it fresh.

Ozzy & Drix for the Game Boy Advance was released in 2002, developed by Digital Eclipse and published by Midway Games. It arrived during a period when licensed platformers were common on the handheld, often drawing from animated series or films. The game is based on the "Ozzy & Drix" cartoon, itself a spin-off from the film "Osmosis Jones," and it fits right in with other action titles of that era.
You control Ozzy, a white blood cell, who punches and kicks through various environments inside the human body, while Drix, a cold pill, assists by freezing enemies and interacting with objects. The main goal is to fight off viruses and bacteria, navigating through themed areas like the lungs or bloodstream. Signature mechanics include cooperative actions where you switch between characters to solve environmental puzzles, screen by screen exploration with some light backtracking, and collecting health upgrades and ability power ups. The pacing is straightforward, though some enemy patterns require timing, and the overall difficulty remains manageable. It feels like a compact, hands on adventure that captures the odd charm of its source material.

Download Ozzy & Drix (U)(Independent) ROM
You can download this ROM to play Ozzy & Drix (U)(Independent) offline using an Game Boy Advance emulator (Top Emulators).
*This ROM is provided for backup and educational purposes only.