Play Spider-Man and Venom - Separation Anxiety (USA, Europe) Online
You smash through waves of goons as Spidey or Venom—his tendrils wreck everything—then call in an Avenger when things get wild. The symbiote mutants get weirder every level.
Ever played one of those old-school beat 'em ups where you just plow through waves of enemies? Separation Anxiety is like that, but with Spider-Man and Venom—and it’s way messier than you’d expect. Venom gets kidnapped, some shady folks rip five symbiotes out of him, and now those things are loose in the city. So, of course, he teams up with Spidey (reluctantly, I’m guessing) to clean up the mess.
You pick either Spider-Man or Venom, and honestly, Venom feels beefier—his tendrils wreck everything. The levels are classic side-scrolling chaos, smashing through thugs and weird symbiote mutants. The cool part? You can call in an Avenger for a one-time assist. Iron Man blasts a whole screen, Hulk smashes—it’s overkill, but in the best way.
And that final boss? No spoilers, but let’s just say it’s not who you’d expect. The game’s janky in that 90s Genesis way, but if you love comic book brawlers, this one’s a weird little gem.
Download Spider-Man and Venom - Separation Anxiety (USA, Europe) ROM
You can download this ROM to play Spider-Man and Venom - Separation Anxiety (USA, Europe) offline using an Sega Genesis (Mega Drive) emulator (Top Emulators).
*This ROM is provided for backup and educational purposes only.
