Play Spider-Man - Mysterio's Menace (U)(Mode7) Online

Spider-Man: Mysterio's Menace came out for the Game Boy Advance in 2001, developed by Vicarious Visions and published by Activision. It was one of the earlier Spider-Man games on the platform, arriving when handhelds were really starting to show what they could do with action and color. The game doesn't try to reinvent the wheel; it just gives you a solid side-scrolling adventure with a classic villain at the center.

You play as Spider-Man, swinging and fighting through a series of levels to stop Mysterio's crime spree across the city. The action is straightforward: you punch, kick, and web your way through enemies, using your spider-sense to avoid attacks. Levels are broken into distinct screens, and you often backtrack or hunt for keys to open up new areas. The pacing is brisk, though some sections can feel repetitive, and the difficulty spikes noticeably in later stages. It feels like a compact, no-nonsense take on being Spider-Man, where your reflexes and familiarity with the moves matter most.