Play Unnatural Selection Online – MS-DOS Game

Game Overview

Unnatural Selection is a unique strategy-simulation game for MS-DOS where players step into the role of a scientist tasked with reclaiming a chain of islands from genetically engineered monsters. The gameplay is split into two distinct phases: first, a breeding phase where you experiment with food, drugs, and radiation to mutate and enhance creatures for combat; and second, a battle phase where your creations face off against the rogue scientist’s monsters in tactical skirmishes. The game’s blend of genetic manipulation and strategic combat offers a creative twist on the monster-breeding genre.

Released during the heyday of PC experimentation in the 1990s, Unnatural Selection stands out for its darkly humorous premise and hands-on approach to creature design. Players must balance traits like speed, aggression, and fertility to outbreed and outfight their opponent, making each playthrough unpredictable. Its mix of lab-based tinkering and battlefield strategy provides a compelling challenge for fans of tactical and simulation games alike.
Each game uses different controls, most DOS games use the keyboard arrows. Some will use the mouse , "Alt" ,"Enter" and "Space bar".