Play Spider-Man 2 : The Sinister Six Online

Spider-Man 2: The Sinister Six came out for the Game Boy Color in 2001, published by Activision. It was one of those late-era GBC titles that tried to squeeze a bit more action out of the hardware before the Advance took over. You play as Spider-Man, swinging and brawling your way through a New York under siege by Doc Ock and his assembled team of villains.

You control Spider-Man through side-scrolling levels, using punches, kicks, and web attacks to clear rooms of enemies. The main goal is to hunt down and defeat each member of the Sinister Six. Signature mechanics include screen-by-screen exploration, where you often backtrack to access new areas, and environmental interactions like webbing up objects or dodging stage hazards. The pacing is brisk, though some boss fights demand precise timing. It feels like a compact, hands-on brawler where every punch and swing carries weight.