Play Dr Mario World - House Calls Online

Dr. Mario World - House Calls was a Super Nintendo Entertainment System release, though it never saw a wide commercial launch. It was developed by Nintendo, building on the familiar puzzle action of the original Dr. Mario but with a few twists for the 16-bit era.

You control Dr. Mario, dropping colored capsules into a bottle to match and eliminate viruses. The main goal is to clear each stage before the bottle fills up. Signature mechanics include rotating capsules mid-fall and chaining combos for bigger clears. The pacing is fast, with levels quickly escalating in complexity and speed. It feels like a constant, satisfying race against a rising tide of germs.